In this practical you’ll practice “data wrangling” with the dplyr
and tidyr
packages (part of the `tidyverse collection of packages).
By the end of this practical you will know how to:
File | Rows | Columns |
---|---|---|
trial_act.csv | 2139 | 27 |
trial_act_demo_fake.csv | 2139 | 3 |
Package | Installation |
---|---|
tidyverse |
install.packages("tidyverse") |
Function | Package | Description |
---|---|---|
rename() |
dplyr |
Rename columns |
select() |
dplyr |
Select columns based on name or index |
filter() |
dplyr |
Select rows based on some logical criteria |
arrange() |
dplyr |
Sort rows |
mutate() |
dplyr |
Add new columns |
case_when() |
dplyr |
Recode values of a column |
group_by(), summarise() |
dplyr |
Group data and then calculate summary statistics |
left_join() |
dplyr |
Combine multiple data sets using a key column |
spread() |
tidyr |
Convert long data to wide format - from rows to columns |
gather() |
tidyr |
Convert wide data to long format - from columns to rows |
# Wrangling with dplyr and tidyr ---------------------------
library(tidyverse) # Load tidyverse for dplyr and tidyr
# Load baselers data
baselers <- read_csv("https://raw.githubusercontent.com/therbootcamp/baselers/master/inst/extdata/baselers.txt")
# Perform many dplyr operations in a row
baselers %>%
# Change some names
rename(age_y = age,
swimming = rhine) %>%
# Only include people over 30
filter(age_y > 30) %>%
# Calculate some new columns
mutate(weight_lbs = weight * 2.22,
height_m = height / 100,
BMI = weight / height_m ^ 2,
# Make binary version of sex
sex_bin = case_when(
sex == "male" ~ 0,
sex == "female" ~ 1),
# Show when height is greater than 150
height_lt_150 = case_when(
height < 150 ~ 1,
height >= 150 ~ 0)) %>%
# Sort in ascending order of sex, then
# descending order of age
arrange(sex, desc(age_y)))
baselrbootcamp
R project. It should already have the folders 1_Data
and 2_Code
. Make sure that the data files listed in the Datasets
section above are in your 1_Data
folder# Done!
wrangling_practical.R
in the 2_Code
folder.# Done!
Using library()
load the set of packages for this practical listed in the packages section above.
For this practical, we’ll use the trial_act
data, this is the result of a randomized clinical trial comparing the effects of different medications on adults infected with the human immunodeficiency virus (You can learn more about the trial here). Using the following template, load the data into R and store it as a new object called trial_act
.
# Load trial_act.csv from the data folder in your working directory
trial_act <- read_csv(file = "XX")
trial_act <- read_csv(file = "1_Data/trial_act.csv")
trial_act_demo_fake.csv
data as a new dataframe called trial_act_demo
trial_act_demo <- read_csv(file = "1_Data/trial_act_demo_fake.csv")
# Print trial_act object
trial_act
# A tibble: 2,139 x 27
pidnum age wtkg hemo homo drugs karnof oprior z30 zprior preanti
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int> <int>
1 10056 48 89.8 0 0 0 100 0 0 1 0
2 10059 61 49.4 0 0 0 90 0 1 1 895
3 10089 45 88.5 0 1 1 90 0 1 1 707
4 10093 47 85.3 0 1 0 100 0 1 1 1399
5 10124 43 66.7 0 1 0 100 0 1 1 1352
6 10140 46 88.9 0 1 1 100 0 1 1 1181
7 10165 31 73.0 0 1 0 100 0 1 1 930
8 10190 41 66.2 0 1 1 100 0 1 1 1329
9 10198 40 82.6 0 1 0 90 0 1 1 1074
10 10229 35 78.0 0 1 0 100 0 1 1 964
# ... with 2,129 more rows, and 16 more variables: race <int>,
# gender <int>, str2 <int>, strat <int>, symptom <int>, treat <int>,
# offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>, r <int>,
# cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>
summary()
function to print more details on the columns of the datasets.summary(trial_act)
pidnum age wtkg hemo
Min. : 10056 Min. :12.0 Min. : 31.0 Min. :0.000
1st Qu.: 81446 1st Qu.:29.0 1st Qu.: 66.7 1st Qu.:0.000
Median :190566 Median :34.0 Median : 74.4 Median :0.000
Mean :248778 Mean :35.2 Mean : 75.1 Mean :0.084
3rd Qu.:280277 3rd Qu.:40.0 3rd Qu.: 82.6 3rd Qu.:0.000
Max. :990077 Max. :70.0 Max. :159.9 Max. :1.000
homo drugs karnof oprior
Min. :0.000 Min. :0.000 Min. : 70.0 Min. :0.000
1st Qu.:0.000 1st Qu.:0.000 1st Qu.: 90.0 1st Qu.:0.000
Median :1.000 Median :0.000 Median :100.0 Median :0.000
Mean :0.661 Mean :0.131 Mean : 95.4 Mean :0.022
3rd Qu.:1.000 3rd Qu.:0.000 3rd Qu.:100.0 3rd Qu.:0.000
Max. :1.000 Max. :1.000 Max. :100.0 Max. :1.000
z30 zprior preanti race gender
Min. :0.00 Min. :1 Min. : 0 Min. :0.000 Min. :0.000
1st Qu.:0.00 1st Qu.:1 1st Qu.: 0 1st Qu.:0.000 1st Qu.:1.000
Median :1.00 Median :1 Median : 142 Median :0.000 Median :1.000
Mean :0.55 Mean :1 Mean : 379 Mean :0.288 Mean :0.828
3rd Qu.:1.00 3rd Qu.:1 3rd Qu.: 740 3rd Qu.:1.000 3rd Qu.:1.000
Max. :1.00 Max. :1 Max. :2851 Max. :1.000 Max. :1.000
str2 strat symptom treat
Min. :0.000 Min. :1.00 Min. :0.000 Min. :0.000
1st Qu.:0.000 1st Qu.:1.00 1st Qu.:0.000 1st Qu.:1.000
Median :1.000 Median :2.00 Median :0.000 Median :1.000
Mean :0.586 Mean :1.98 Mean :0.173 Mean :0.751
3rd Qu.:1.000 3rd Qu.:3.00 3rd Qu.:0.000 3rd Qu.:1.000
Max. :1.000 Max. :3.00 Max. :1.000 Max. :1.000
offtrt cd40 cd420 cd496
Min. :0.000 Min. : 0 Min. : 49 Min. : 0
1st Qu.:0.000 1st Qu.: 264 1st Qu.: 269 1st Qu.: 209
Median :0.000 Median : 340 Median : 353 Median : 321
Mean :0.363 Mean : 351 Mean : 371 Mean : 329
3rd Qu.:1.000 3rd Qu.: 423 3rd Qu.: 460 3rd Qu.: 440
Max. :1.000 Max. :1199 Max. :1119 Max. :1190
NA's :797
r cd80 cd820 cens
Min. :0.000 Min. : 40 Min. : 124 Min. :0.000
1st Qu.:0.000 1st Qu.: 654 1st Qu.: 632 1st Qu.:0.000
Median :1.000 Median : 893 Median : 865 Median :0.000
Mean :0.627 Mean : 987 Mean : 935 Mean :0.244
3rd Qu.:1.000 3rd Qu.:1207 3rd Qu.:1146 3rd Qu.:0.000
Max. :1.000 Max. :5011 Max. :6035 Max. :1.000
days arms
Min. : 14 Min. :0.00
1st Qu.: 727 1st Qu.:1.00
Median : 997 Median :2.00
Mean : 879 Mean :1.52
3rd Qu.:1091 3rd Qu.:3.00
Max. :1231 Max. :3.00
summary(trial_act_demo)
pidnum exercise education
Min. : 10056 Min. :0.0 Length:2139
1st Qu.: 81446 1st Qu.:1.0 Class :character
Median :190566 Median :1.0 Mode :character
Mean :248778 Mean :2.2
3rd Qu.:280277 3rd Qu.:3.0
Max. :990077 Max. :7.0
In this practical you will do many operations on dataframes. If you can, try to Remember when using dplyr
, you can chain multiple functions together with the pipe %>%
. When giving your answers to the questions in this practical, see how many operations you can chain with the pipe!
baselers <- read_csv("1_Data/baselers.csv")
# Method 1: Separate operations
baselers <- baselers %>%
rename(Age_y = age) # Change age to Age__y
baselers <- baselers %>%
mutate(food_p = food / income) # calculate food_p
baselers <- baselers %>%
filter(sex == "m") # Only include males
# Method 2: Chain with the pipe!
baselers <- read_csv("1_Data/baselers.csv")
baselers <- baselers %>%
rename(Age_y = age) %>% # Change age to Age__y
mutate(food_p = food / income) %>% # calculate food_p
filter(sex == "m") # Only include males
trial_act
data with names(XXX)
names(XXX)
names(trial_act)
[1] "pidnum" "age" "wtkg" "hemo" "homo" "drugs" "karnof"
[8] "oprior" "z30" "zprior" "preanti" "race" "gender" "str2"
[15] "strat" "symptom" "treat" "offtrt" "cd40" "cd420" "cd496"
[22] "r" "cd80" "cd820" "cens" "days" "arms"
rename()
, change the column name wtkg
in the trial_act
dataframe to weight_kg
. Be sure to assign the result back to trial_act
to change it!# Change the name to weight_kg from wtkg
trial_act <- trial_act %>%
rename(XX = XX)
trial_act <- trial_act %>%
rename(weight_kg = wtkg)
trial_act
dataframe again, do you now see the column weight_kg
?names(trial_act)
[1] "pidnum" "age" "weight_kg" "hemo" "homo"
[6] "drugs" "karnof" "oprior" "z30" "zprior"
[11] "preanti" "race" "gender" "str2" "strat"
[16] "symptom" "treat" "offtrt" "cd40" "cd420"
[21] "cd496" "r" "cd80" "cd820" "cens"
[26] "days" "arms"
age
to age_y
(to specify that age is in years).trial_act <- trial_act %>%
rename(age_y = age)
select()
function, select only the column age_y
and print the result (but don’t assign it to anything). Do you see only the age_y
column now?XXX %>%
select(XXX)
trial_act %>%
select(age_y)
# A tibble: 2,139 x 1
age_y
<int>
1 48
2 61
3 45
4 47
5 43
6 46
7 31
8 41
9 40
10 35
# ... with 2,129 more rows
Using select()
select the columns pidnum
, age_y
, gender
, and weight_kg
(but don’t assign the result to anything)
Now it’s time to create a new dataframe! Select the columns pidnum
, arms
, cd40
, cd420
, and cd496
and assign the result to a new object called CD4_wide
. The cd40
, cd420
, and cd496
columns show patient’s CD4 T cell counts at baseline, 20 weeks, and 96 weeks. After you create CD4_wide
, print it to make sure it worked!
XX <- trial_act %>%
select(XX, XX, XX, XX, ...)
CD4_wide <- trial_act %>%
select(`pidnum`, `arms`, `cd40`, `cd420`, `cd496`)
starts_with()
? Try adapting the following code to get the same result you got before.CD4_wide <- trial_act %>%
select(pidnum, arms, starts_with("XXX"))
CD4_wide <- trial_act %>%
select(pidnum, arms, starts_with("cd"))
pidnum
and age
. Create this dataframe by selecting all columns except pidnum
and age
(hint: use the notation select(-XXX, -XXX))
to select everything except specified columnsmutate()
function, add the column age_m
which shows each patient’s age in months instead of years (Hint: Just multiply age_y
by 12!)trial_act <- trial_act %>%
mutate(XX = XX * 12)
trial_act <- trial_act %>%
mutate(age_m = age_y * 12)
mutate
, add the following new columns to trial_act
. (Try combining these into one call to the mutate()
function!)weight_lb
: Weight in lbs instead of kilograms. You can do this by multiplying weight_kg
by 2.2.cd_change_20
: Change in CD4 T cell count from baseline to 20 weeks. You can do this by taking cd420 - cd40
cd_change_960
: Change in CD4 T cell count from baseline to 96 weeks. You can do this by taking cd496 - cd40
XXX <- XXX %>%
mutate(weight_lb = XXX,
cd_change_20 = XXX,
XXX = XXX)
trial_act <- trial_act %>%
mutate(weight_lb = weight_kg * 2.2,
cd_change_20 = cd420 - cd40,
cd_change_960 = cd496 - cd40)
gender
column, you will see that it is numeric (0s and 1s). Using the mutate()
and case_when()
functions, create a new column called gender_char
which shows the gender as a string, where 0 = “female” and 1 = “male”:# Create gender_char which shows gender as a stringh
trial_act <- trial_act %>%
mutate(
gender_char = case_when(
gender == XX ~ "XX",
gender == XX ~ "XX"))
trial_act <- trial_act %>%
mutate(
gender_char = case_when(
gender == 0 ~ "female",
gender == 1 ~ "male"))
arms
is also numeric and not very meaningful. Create a new column arms_char
contains the names of the arms. Here is a table of the mappingarms | arms_char |
---|---|
0 | zidovudine |
1 | zidovudine and didanosine |
2 | zidovudine and zalcitabine |
3 | didanosine |
trial_act <- trial_act %>%
mutate(
arms_char = case_when(
arms == 0 ~ "zidovudine",
arms == 1 ~ "zidovudine and didanosine",
arms == 2 ~ "zidovudine and zalcitabine",
arms == 3 ~ "didanosine"))
mutate()
. That is, in one block of code, create age_m
, weight_lb
, cd_change_20
, cd_change_960
, gender_char
and over50
using the mutate()
function only once. Here’s how your code should look:trial_act <- trial_act %>%
mutate(
age_m = XXX,
weight_lb = XXX,
cd_change_20 = XXX,
XXX = XXX,
XXX = case_when(XXX),
XXX = case_when(XXX)
)
trial_act <- trial_act %>%
mutate(
agem = age_y * 12,
weight_lb = weight_kg * 2.2,
cd_change_20 = cd420 - cd40,
cd_change_960 = cd496 - cd40,
gender_char = case_when(
gender == 0 ~ "female",
gender == 1 ~ "male"),
arms_char = case_when(
arms == 0 ~ "zidovudine",
arms == 1 ~ "zidovudine and didanosine",
arms == 2 ~ "zidovudine and zalcitabine",
arms == 3 ~ "didanosine")
)
arrange()
function, arrange the trial_act
data in ascending order of age_y
(from lowest to highest). After you do, print the data to make sure it worked!trial_act <- trial_act %>%
arrange(XXX)
trial_act <- trial_act %>%
arrange(age_y)
trial_act
# A tibble: 2,139 x 34
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 940533 12 41.4 1 0 0 100 0 0 1
2 950037 12 53.1 1 0 0 100 0 1 1
3 950056 12 31 1 0 0 100 0 1 1
4 910034 13 32.7 1 0 0 100 0 1 1
5 940534 13 62.9 1 0 0 100 0 0 1
6 960014 13 48.5 1 0 0 100 0 0 1
7 310767 14 65 1 0 0 100 0 1 1
8 920050 14 54.2 1 0 0 100 0 1 1
9 940544 14 41.1 1 0 0 100 0 0 1
10 950061 14 64.3 1 0 0 100 0 1 1
# ... with 2,129 more rows, and 24 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>
age_y
(from highest to lowest). After, look the data to make sure it worked. To arrange data in descending order, just include desc()
around the variable. E.g.; data %>% arrrange(desc(height))
trial_act <- trial_act %>%
arrange(desc(age_y))
trial_act
# A tibble: 2,139 x 34
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 11438 70 73.9 0 1 0 100 0 1 1
2 211360 70 63.1 0 1 0 90 0 0 1
3 211284 69 81.6 0 1 0 100 0 0 1
4 50580 68 90.5 0 1 1 100 0 1 1
5 81127 68 70.8 0 1 0 90 0 1 1
6 10924 67 71 0 1 0 100 0 0 1
7 241150 67 82.1 0 1 0 90 0 0 1
8 50662 66 84.4 0 1 0 100 0 0 1
9 11987 65 77.2 0 1 0 90 0 0 1
10 140797 65 60.5 0 1 0 90 0 0 1
# ... with 2,129 more rows, and 24 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>
arrange()
. Now sort the data by arms (arms
) and then age_y (age_y
). Print the result to make sure it looks right!trial_act <- trial_act %>%
arrange(XXX, XXX)
trial_act <- trial_act %>%
arrange(arms, age_y)
trial_act
# A tibble: 2,139 x 34
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 960014 13 48.5 1 0 0 100 0 0 1
2 960031 14 48.3 1 0 0 100 0 0 1
3 990071 14 60 1 0 0 100 0 0 1
4 980042 16 63 1 0 0 100 0 1 1
5 171040 17 51.3 0 0 0 90 0 0 1
6 990026 17 103. 1 0 0 100 0 1 1
7 310234 18 57.3 1 0 0 100 0 1 1
8 940519 18 56.8 1 0 0 100 0 1 1
9 211314 19 50.8 0 0 0 90 0 0 1
10 340767 19 74.8 0 1 0 100 0 0 1
# ... with 2,129 more rows, and 24 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>
filter()
filter()
function, filter only the rows from males (Hint: gender_char == "male"
)trial_act %>%
filter(XXX == "XXX")
trial_act %>%
filter(gender_char == "male")
# A tibble: 1,771 x 34
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 960014 13 48.5 1 0 0 100 0 0 1
2 960031 14 48.3 1 0 0 100 0 0 1
3 990071 14 60 1 0 0 100 0 0 1
4 980042 16 63 1 0 0 100 0 1 1
5 990026 17 103. 1 0 0 100 0 1 1
6 940519 18 56.8 1 0 0 100 0 1 1
7 340767 19 74.8 0 1 0 100 0 0 1
8 211007 20 72.7 0 1 0 90 0 1 1
9 261065 20 57.3 0 1 0 100 0 0 1
10 490308 20 72 0 1 0 100 0 0 1
# ... with 1,761 more rows, and 24 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>
trial_act_male
that only contains rows from males (hint: just assign what you did in the previous question to a new object!). After you create trial_act_male
, print it to make sure it only contains data from males!trial_act_male <- trial_act %>%
filter(gender_char == "male")
trial_act_male
# A tibble: 1,771 x 34
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 960014 13 48.5 1 0 0 100 0 0 1
2 960031 14 48.3 1 0 0 100 0 0 1
3 990071 14 60 1 0 0 100 0 0 1
4 980042 16 63 1 0 0 100 0 1 1
5 990026 17 103. 1 0 0 100 0 1 1
6 940519 18 56.8 1 0 0 100 0 1 1
7 340767 19 74.8 0 1 0 100 0 0 1
8 211007 20 72.7 0 1 0 90 0 1 1
9 261065 20 57.3 0 1 0 100 0 0 1
10 490308 20 72 0 1 0 100 0 0 1
# ... with 1,761 more rows, and 24 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>
trial_act %>%
filter(age_y < 60)
# A tibble: 2,110 x 34
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 960014 13 48.5 1 0 0 100 0 0 1
2 960031 14 48.3 1 0 0 100 0 0 1
3 990071 14 60 1 0 0 100 0 0 1
4 980042 16 63 1 0 0 100 0 1 1
5 171040 17 51.3 0 0 0 90 0 0 1
6 990026 17 103. 1 0 0 100 0 1 1
7 310234 18 57.3 1 0 0 100 0 1 1
8 940519 18 56.8 1 0 0 100 0 1 1
9 211314 19 50.8 0 0 0 90 0 0 1
10 340767 19 74.8 0 1 0 100 0 0 1
# ... with 2,100 more rows, and 24 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>
filter()
and call it trial_act_Tracy
. After you create the dataframe, print it to make sure it looks correct!trial_act_Tracy <- XXX %>%
filter(XXX > XXX & XXX == XXX)
trial_act_Tracy <- trial_act %>%
filter(age_y > 40 & gender_char == "female")
left_join()
The trial_act_demo.csv
file contains additional (fictional) demographic data about the patients, namely the number of days of exercise they get per week, and their highest level of education. Our goal is to add the demographic information to our trial_act
data.
In order to combine the two dataframes, we need to find one ‘key’ column that we can use to match rows. Look at both the trial_act
and trial_act_demo
dataframes. Which column can we use as the ‘key’ column?
Use the left_join()
function to combine the trial_act
and trial_act_demo
datasets, set the by
argument to the name of the key column that is common in both data sets. Assign the result to trial_act
.
trial_act <- trial_act %>%
left_join(XX, by = "XX")
trial_act <- trial_act %>%
left_join(trial_act_demo, by = "pidnum")
trial_act
dataframe. Do you now see the demographic data?trial_act
# A tibble: 2,139 x 36
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 960014 13 48.5 1 0 0 100 0 0 1
2 960031 14 48.3 1 0 0 100 0 0 1
3 990071 14 60 1 0 0 100 0 0 1
4 980042 16 63 1 0 0 100 0 1 1
5 171040 17 51.3 0 0 0 90 0 0 1
6 990026 17 103. 1 0 0 100 0 1 1
7 310234 18 57.3 1 0 0 100 0 1 1
8 940519 18 56.8 1 0 0 100 0 1 1
9 211314 19 50.8 0 0 0 90 0 0 1
10 340767 19 74.8 0 1 0 100 0 0 1
# ... with 2,129 more rows, and 26 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>, exercise <int>,
# education <chr>
Remember the CD4_wide
dataframe you created before? Currently it is in the wide format, where each row is a patient, where key data (different CD4 T cell counts) are in different columns like this:
# Data is in a 'wide' format
CD4_wide
# A tibble: 2,139 x 5
pidnum arms cd40 cd420 cd496
<int> <int> <int> <int> <int>
1 960014 0 283 271 NA
2 960031 0 481 428 519
3 990071 0 166 169 28
4 980042 0 299 214 124
5 171040 0 549 415 436
6 990026 0 373 218 NA
7 310234 0 445 371 338
8 940519 0 276 150 34
9 211314 0 298 267 NA
10 340767 0 503 452 NA
# ... with 2,129 more rows
Our goal is to convert this data to a ‘long’ format, where each row represents a single CD4 T cell count for a specific patient, like this:
# This is the same data in 'long' format
CD4_long
# A tibble: 6,417 x 4
pidnum arms time value
<int> <int> <chr> <int>
1 960014 0 cd40 283
2 960031 0 cd40 481
3 990071 0 cd40 166
4 980042 0 cd40 299
5 171040 0 cd40 549
6 990026 0 cd40 373
7 310234 0 cd40 445
8 940519 0 cd40 276
9 211314 0 cd40 298
10 340767 0 cd40 503
# ... with 6,407 more rows
gather()
function, create a new dataframe called CD4_long
that shows the CD4_wide
data in the ‘long’ format. To do this, use the following template. Set the grouping column to time
and the new data column to value
.CD4_long <- CD4_wide %>%
gather(XX, # New grouping column
XX, # New data column
-pidnum, -arms) # Names of columns to replicate
CD4_long <- CD4_wide %>%
gather(time, # New grouping column
value, # New data column
-pidnum, -arms) # Names of columns to replicate
CD4_long
dataframe! Do you now see that each row is a specific observation for a patient?CD4_long
# A tibble: 6,417 x 4
pidnum arms time value
<int> <int> <chr> <int>
1 960014 0 cd40 283
2 960031 0 cd40 481
3 990071 0 cd40 166
4 980042 0 cd40 299
5 171040 0 cd40 549
6 990026 0 cd40 373
7 310234 0 cd40 445
8 940519 0 cd40 276
9 211314 0 cd40 298
10 340767 0 cd40 503
# ... with 6,407 more rows
spread()
function to convert the long data bring the data back into the wide format! To do this, make the first argument time
, and the second argument value
CD4_long %>%
spread(XX, # Grouping column
XX) # Value columnn
CD4_long %>%
spread(time, value)
# A tibble: 2,139 x 5
pidnum arms cd40 cd420 cd496
<int> <int> <int> <int> <int>
1 10056 2 422 477 660
2 10059 3 162 218 NA
3 10089 3 326 274 122
4 10093 3 287 394 NA
5 10124 0 504 353 660
6 10140 1 235 339 264
7 10165 0 244 225 106
8 10190 0 401 366 453
9 10198 3 214 107 8
10 10229 0 221 132 NA
# ... with 2,129 more rows
trial_A
from trial_act
with the following restrictions:drugs == 1
)cd40
were greater than 250 and less than 400.trial_A <- trial_act %>%
filter(drugs == 1,
age_y < 60,
cd40 > 250 & cd40 < 400)
trial_A
# A tibble: 126 x 36
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 630023 26 86.2 0 0 1 90 0 0 1
2 10378 27 67.3 0 0 1 90 0 1 1
3 320475 27 66.6 0 0 1 90 0 0 1
4 71333 29 73.9 0 1 1 100 0 0 1
5 140809 29 70 0 1 1 100 0 0 1
6 630030 29 88.2 0 0 1 100 0 0 1
7 190395 33 68 0 0 1 100 0 1 1
8 320365 34 86.0 0 0 1 100 0 0 1
9 540015 34 72.6 0 0 1 100 0 0 1
10 180917 35 77.7 0 0 1 90 0 1 1
# ... with 116 more rows, and 26 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>, exercise <int>,
# education <chr>
trial_act
called drugs_char
which is "User"
when drugs == 1, and "Non User"
when drugs == 0.trial_act <- trial_act %>%
mutate(drugs_char = case_when(
drugs == 1 ~ "User",
drugs == 0 ~ "Non User"
))
trial_act
# A tibble: 2,139 x 37
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 960014 13 48.5 1 0 0 100 0 0 1
2 960031 14 48.3 1 0 0 100 0 0 1
3 990071 14 60 1 0 0 100 0 0 1
4 980042 16 63 1 0 0 100 0 1 1
5 171040 17 51.3 0 0 0 90 0 0 1
6 990026 17 103. 1 0 0 100 0 1 1
7 310234 18 57.3 1 0 0 100 0 1 1
8 940519 18 56.8 1 0 0 100 0 1 1
9 211314 19 50.8 0 0 0 90 0 0 1
10 340767 19 74.8 0 1 0 100 0 0 1
# ... with 2,129 more rows, and 27 more variables: preanti <int>,
# race <int>, gender <int>, str2 <int>, strat <int>, symptom <int>,
# treat <int>, offtrt <int>, cd40 <int>, cd420 <int>, cd496 <int>,
# r <int>, cd80 <int>, cd820 <int>, cens <int>, days <int>, arms <int>,
# age_m <dbl>, weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>, exercise <int>,
# education <chr>, drugs_char <chr>
trial_B
from trial_act
with the following restrictions:cd40
) and after 96 weeks (cd496
)trial_B <- trial_act %>%
filter(
cd496 - cd40 > 200,
drugs == 1
)
trial_B
# A tibble: 8 x 37
pidnum age_y weight_kg hemo homo drugs karnof oprior z30 zprior
<int> <int> <dbl> <int> <int> <int> <int> <int> <int> <int>
1 220489 45 70.9 0 0 1 100 0 0 1
2 140744 30 81.2 0 1 1 100 0 0 1
3 10962 41 81.9 0 0 1 90 0 0 1
4 50580 68 90.5 0 1 1 100 0 1 1
5 10881 36 81.6 0 1 1 100 0 1 1
6 250197 49 86.2 0 1 1 90 0 0 1
7 50572 28 84.4 0 1 1 90 0 0 1
8 50623 35 77 0 1 1 100 0 0 1
# ... with 27 more variables: preanti <int>, race <int>, gender <int>,
# str2 <int>, strat <int>, symptom <int>, treat <int>, offtrt <int>,
# cd40 <int>, cd420 <int>, cd496 <int>, r <int>, cd80 <int>,
# cd820 <int>, cens <int>, days <int>, arms <int>, age_m <dbl>,
# weight_lb <dbl>, cd_change_20 <int>, cd_change_960 <int>,
# gender_char <chr>, arms_char <chr>, agem <dbl>, exercise <int>,
# education <chr>, drugs_char <chr>